日韩精品久久一区二区三区_亚洲色图p_亚洲综合在线最大成人_国产中出在线观看_日韩免费_亚洲综合在线一区

Global EditionASIA 中文雙語Fran?ais
World
Home / World / Americas

Trial for COVID-19 pill moving into next stage

By ANGUS MCNEICE in London | China Daily | Updated: 2020-07-10 08:17
Share
Share - WeChat
A member of medical staff takes a swab from a person in a car at an NHS coronavirus disease (COVID-19) testing facility, as the spread of the coronavirus disease (COVID-19) continues, in Wolverhampton, Britain, April 7, 2020. [Photo/Agencies]

A drug testing platform in the United Kingdom is launching the second phase of human trials for an experimental antiviral treatment that could be given to COVID-19 patients in pill form.

The drug, which is called EIDD-2801, was initially developed to treat influenza, and researchers involved in the trial say the treatment "could change the future of the pandemic" if it displays efficacy against novel coronavirus infection.

The drug works in a similar way to remdesivir, an antiviral treatment that has shown early promise in combating severe symptoms in COVID-19 patients. EIDD-2801 has an advantage over remdesivir because it can be given to patients orally, instead of through an injection. This means that patients could take the drug at home, earlier in the course of infection.

The trial, which recently gained approval from the UK drug regulator, will be conducted at a clinical research unit at the Royal Liverpool University Hospital.

"We approved this trial, as it not only innovates in the early clinical trial process, which is crucial in the current pandemic, but it is also robust and safe, providing opportunities for more rapid progress toward suitable treatment options," said Siu Ping Lam, who is the director of licensing at the UK Medicines and Healthcare Products Regulatory Agency.

EIDD-2801 was proved to be safe in humans following phase one human trials in the UK in April. The company that holds licensing for the drug, the United States-based Ridgeback Biotherapeutics, began pursuing trials in people after promising results in animal testing.

In animal studies, EIDD-2801 was shown to improve pulmonary function, decrease weight loss and reduce the viral load in the lungs.

The drug works by introducing a series of copying errors during viral RNA replication, essentially killing a virus by forcing a cascade of mutations. In a laboratory setting, EIDD-2801 has been shown to trigger this antiviral reaction in several members in the coronavirus family, including SARS, MERS, and SARS-CoV-2, which is another name for the novel coronavirus.

EIDD-2801 is the first COVID-19 therapy set for human trials under the recently-formed UK-based COVID-19 drug testing platform AGILE. The platform includes researchers from Liverpool, Southampton and Lancaster universities, as well as the Liverpool School of Tropical Medicine and the Southampton Clinical Trials Unit, among other partners.

'Bridge the gap'

Saye Khoo, who is a professor in molecular and clinical pharmacology at Liverpool University and is chief investigator on AGILE, said he is optimistic that the platform "will accelerate the development of treatments for COVID-19".

Khoo said AGILE will bridge the gap between preclinical drug discovery and large-scale testing, thereby "rapidly identifying drugs that have the best chance of success".

"In the ongoing pandemic, we need to find innovative ways to identify safe and effective treatments as soon as possible," he said.

Most Viewed in 24 Hours
Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
主站蜘蛛池模板: 黄色一级大片在线免费看产 | 成人午夜免费视频毛片 | 狠狠五月| 国产小视频免费在线观看 | 国产欧美日韩不卡一区二区三区 | 精品国产一区二区三区久久久蜜臀 | 一区二区三区在线 | 日本高清色惰www在线视频 | 国产福利不卡视频在免费播放 | 久久久久久久蜜桃 | 久久精品中文 | 无码乱人伦一区二区亚洲 | 久久久久久久成人 | 国产一级做a爰片久久毛片 欧美一区欧美二区 | 精品国内视频 | 国产高清一区二区三区 | 国产免费观看一区 | 亚洲欧洲日韩国产aa色大片 | 欧美福利视频在线观看 | 亚洲一区二区三区日本久久九 | 日韩有码一区 | 欧美一区二区精品 | 久久久久国产精品免费免费搜索 | 亚洲美女一区二区三区 | 国产精品视频第一区二区三区 | 亚洲一区二区中文字幕 | 中文天堂av | 天天射天天操天天干 | 男女www视频| 99re视频| 精品日韩欧美一区二区三区在线播放 | 密室逃脱第一季免费观看完整在线 | 久久精品 | 欧美一极视频 | 成人一区二区在线 | 丁香九月婷婷 | 久久综合九色综合欧美狠狠 | 欧美中文字幕一区二区 | 亚洲午夜电影 | 玖玖啪 | 国产精品一区二区三区四区 |